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09/20/2022: Hu was invited for guest lecture in the Department of Mathematics and Statistics at the University of Victoria

09/20/2022: Hu was invited for guest lecture in the Department of Mathematics and Statistics at the University of Victoria

Deciphering tissue microenvironment from Next Generation Sequencing data

The advent of high-throughput next-generation sequencing (NGS) technologies has transformed our understanding of cell biology and human disease. As NGS has been adopted earliest by the scientific community, its use has now become widespread, and the technology has improved rapidly. At present, it is now common for laboratories to assay genome-wide transcriptomes of thousands of cells in a single scRNA-seq experiment. In addition, technologies that enable the measurement of new information, for example, chromatin accessibility, protein quantification, and spatial location, have been developed. In order to take full advantage of the multi-modality information when analyzing NGS data, new methods are demanded. This seminar will introduce several machine learning algorithms for NGS data analysis with different aims, including cell type classification, spatial domain detection, and tumor microenvironment annotation.

Link: https://www.uvic.ca/science/math-statistics/home/home/events/seminars/statistics/index.php